The CILTEP stack is an all-natural nootropic stack that induces long-term potentiation (LTP). CILTEP stands for “chemically induced long-term potentiation”. LTP is a consistent strengthening of signal transmissions between neurons as a result of stimulating them simultaneously. LTP is one of the most significant cellular instruments in enhancing memory and learning.
Abelard Lindsay, a world famous biohacker, developed the CILTEP stack in 2011. What started off as a personal pet project developed into an immensely popular concoction and is now one of the most talked about nootropic stacks in recent history.
CILTEP works by using two primary supplements: a phosphodiesterase-4 (PDE-4) inhibitor and a cyclic adenosine monophosphate (cAMP) booster. cAMP is a critical messenger system for intracellular signal transmission. This system is vital for cells to respond appropriately to hormones and other signals. By increasing the level of cAMP within the brain, it will enhance neural activities.
As an enzyme, Phosphodiesterase-4 hydrolyzes cAMP molecules into inactive adenosine monophosphate (AMP). By inhibiting the degradative actions of this enzyme, Most CILTEP stacks contain artichoke extract to achieve this as it is known to be the most effective and the safest.
The second supplement is to enhance cAMP concentration in the brain naturally. Forskolin (a chemical found from extracting the root of the Coleus Forskohlii plant) is the only known supplement to increase the level of cAMP naturally. This ingredient activates the adenylyl cyclase enzyme which intensifies the intracellular levels of cAMP.
As a result, taking both artichoke extract and forskolin will lead to LTP.
The most notable benefit from taking the CILTEP stack is enhanced memory (both short-term and long-term) and increased speed of learning. Some users also reported having better focus and alertness lasting as long as 8 to 14 hours. Combining these benefits makes the CILTEP stack one of the best nootropic combinations out there for studying and learning.
Apart from drowsiness and fatigue, there are not many reported side effects of CILTEP. Some people believe that dopamine depletion causes this fatigue. You could add a dopamine precursor to counter this. To reduce drowsiness, some people add a vitamin B complex or a small dose of caffeine to this stack.
Because the non-active plant compound in forskolin can increase liver enzymes, you should purchase this supplement in the highest potency available. Doing this will enable you to achieve the most of forskolin’s benefit while minimizing the adverse effect of its non-active matter.
PDE-4 inhibitors can sometimes cause nausea when you ingest it in high amounts. Therefore, you should only take artichoke extract within the standard dosage.
The dosage suitable for you will vary depending on which supplements you choose to use in your CILTEP stack. Most people starting on this stack begin with 200 mg to 300 mg of artichoke extract and about 4 mg of forskolin per day. You should monitor your body’s reaction and tolerance to this before increasing the amount.
You can increase the dosage of artichoke extract up to 900 mg and forskolin by 20 mg, depending on the potency of the forskolin you use. However, you should not exceed a total dosage of over 1 gm every day. You might also want to take CILTEP on every alternate day.
The CILTEP stack is one of the most talked about nootropic stacks in recent history. It has received overwhelmingly positive feedback from many users. However, it is always wise to consult a medical professional before starting any new supplement routine.