Adrafinil Side Effects & Dangers

Adrafinil Side Effects

Although nearly all Nootropics are relatively non-hazardous and well-tolerated, Adrafinil is known to carry the possibility of certain side effects. The majority of these side effects usually won’t be apparent except at high doses; however, it’s vital for all its users to remain well informed about all of the likely side effects and dangers associated with its intake so that they can opt for the best choice.

Adrafinil doesn’t generally cause stimulant-resembling side effects (,e.g. high blood pressure and heart ailments), but the possibilities are high if the users are already suffering from any preexisting condition. The dangers might be compounded if they consume it in larger dosages, and that is why adherence to its correct usage guidelines is crucial.

S0me of the most common side effects [associated with Adrafinil], which are also relatively mild in nature, are nausea, dizziness, heart palpitations, stomach uneasiness, chest pain, headaches, easy bruising, etc. These usually occur when it is taken in high dosages, and most of these can be tackled by decreasing the dosage quantity and, perhaps, discontinuing use for some time. You can also opt for another nootropic in its place.

The article attempts to overview the most common side effects related to Adrafinil and its interactions with other drugs. The following is a list of its most common side effects:

Heart palpitations: If you’re suffering from any heart ailment or you have a history of heart-related issues then, first and foremost, you must consult your doctor prior to opting for Adrafinil to avoid any heart-related risks. Its users have reported problems like tachycardia and heart palpitations. These usually occur due to the intake of high Adrafinil dosages and should be avoided in case of any preexisting heart conditions.

Skin Issues: Adrafinil is associated with some severe skin conditions, such as Stevens-Johnson-Syndrome, DRESS-Syndrome, and Toxic-Epidermal-Necrolysis.  Although the chances of getting these skin conditions are pretty low, the users are still advised to consider these conditions as medical emergencies. If the users notice any skin blisters, hives, rashes or reddened skin parts, they should instantly consult a skin physician. The skin rashes usually occur as a result of the release of a neurotransmitter called histamine in your body due to the intake of Adrafinil.

Liver Toxicity: Adrafinil is broken down (metabolized) into Modafinil in your liver gland. This entire process puts a lot of strain on your liver and enhances the levels of certain liver enzymes in your body. This excess strain can lead to severe liver toxicity. Adrafinil enhances the levels of liver enzymes such as GGPT, SGPT, SGOT, and hepatic alkaline phosphatase in your body, which severely affects the functioning of your liver. Consequently, all long-term users of this supplement must get their liver monitored regularly. 

Anxiety: Some users are reported to have experienced an increase in anxiety levels. It could be a sign that they’re taking high supplement dosage or the supplement is getting metabolized at a slower rate in their body. You’re again advised to take an appropriate quantity of the nootropic supplement as a preventative measure. If you’re suffering from any preexisting neuropsychiatric ailments then you must consult your physician at the earliest.

Insomnia: Adrafinil was primarily manufactured to promote alertness and, thus, it’s being used to treat extreme sleepiness and exhaustion. Insomnia can be due to the intake of high dosage or because of the late intake during the day. Adrafinil increases the levels of neurotransmitters such as orexin, dopamine, and norepinephrine in your body which leads to insomnia. Insomnia can be lessened by decreasing the dosage quantity and by consuming the supplement during the early mornings. 

Drug Interactions:

Tranquillizers: Adrafinil supplements are not recommended for those who’re suffering from any liver or kidney-related ailments or even epilepsy. Additionally, it’s not advised to take it in concert with any major tranquilizers (,e.g. pimozide, chlorpromazine, haloperidol etc.) which might exacerbate the related ailments.

Caffeine and Adderall: Mixing Adrafinil with other recognized stimulants, such as caffeine and Adderall, isn’t recommended at all. The combinations might exacerbate conditions like insomnia, nausea, and anxiety. You need to consult your doctor prior to opting for this supplement to ensure that you don’t have any preexisting heath conditions or any therapeutic prescription which might interfere with the effects of the supplement.

Alcohol: The combination of Adrafinil with alcohol might prove to be dangerous for your liver gland. The users who are suffering from liver ailments are not at all recommended to take Adrafinil as it increases the levels of liver enzymes in the body. Mixing it with alcohol will put additional strain on your liver which might cause severe liver ailments.

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Erica Silva
Senior Editor
Erica Silva is a blogger by choice. She loves to discover the world around her. She likes to share her discoveries, experiences and express herself through her blogs. Currently, she is associated with DementiaTalk Team.

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