What is it?

Adrafinil is a smart drug that is a precursor to the wildly popular Modafinil. It is metabolized in the body to produce Modafinil internally. A powerful eugeroic nootropic, Adrafinil is used by narcoleptics, students night shift workers and entrepeneurs alike for its cognitive enhancement abilities.

A mild CNS (Central Nervous System) stimulant, Adrafinil is prescribed for sleep disorders, sleep pattern problems, circadian rhythm disorder and more. Although it has not been regulated in the US like Modafinil supplements, its use has proliferated among Americans who are afflicted with cognitive and sleep issues. Many also believe it to be an effective all-natural alternative to mainstream anti-depressants and anti-anxiety meds. It is also given to those who report acute fatigue; for this reason, there is reason to believe that Adrafinil would be advantageous to persons with Fibromyalgia or Chronic Fatigue Syndrome.

Adrafinil’s Rep

Adrafinil’s online profile could hardly be better. gives Adrafinil five stars, noting its cognitive performance capacity as well as its affordability as a supplement. They also note Adrafinil’s 80% bioavailability and calling it a good option for those seeking improved mood and increased motivation.

Other users are less enthusiastic with one Reddit poster urging a virgin user to up their dose slowly, saying, “It is a subtle drug and you might not notice anything initially until you look back over a week or so.” Another poster pointed out that not everyone has the metabolism to convert this pro-drug into Modafinil. Still another warned that its metabolites can cause hepatotoxicity, chemical-driven liver damage.

All in all, the bigger picture seems to be a pretty one. Most nootropic-related online journals have sung Adrafinil’s praises with Consumer Health Digest giving it a three and a half star rating and Nootropics Depot giving it four stars.



Adrafinil use seems to result in a more pronounced presence of Hypocretin, a neuropeptide that influences our alertness and arousal as well as our sensation of feeling awake. An uptake in Hypocretin can result in a larger production of Dopamine, Histamine and Norpinephrine, the three hormones responsible for a feeling of being energized.

If one takes Adrafinil before studying or perusing a Powerpoint presentation at work, the corollary will almost always be more focus and attentiveness. It helps to stabilize your mood by regulating Dopamine levels and causing an uptake in Serotonin.

These are just some of the advantages to taking Adrafinil. The following is a list of its key benefits:

  • Increased Concentration
  • Wakefulness
  • Improved Mood
  • Sharper Focus
  • Relief from Hyperactivity
  • Relief from Depression
  • Relief from Anxiety
  • Better Night’s Sleep
  • Relief from Narcolepsy
  • Increased Productivity
  • Stamina
  • Improved Learning Ability
  • Improved Memory

Side Effects

Side Effects

Adrafinil does come with an array of possible side effects ranging from mild to severe. They are as follows:

  • Irritability
  • Nausea
  • Dry Mouth
  • Anxiety
  • Sleep Issues
  • Bruising Easily
  • Heart Palpitations
  • Hallucinations
  • Chest Pain

If you or anyone you suffer from a preexisting heart condition, you should beware of Adrafinil’s potential to affect your heart. As a stimulant, Adrafinil can increase the probability of you developing additional heart-related conditions. Speak with your doctor before taking your first Adrafinil dosage as it may not be a good idea for you to take the drug at all.

When taken over the course of a long period of time, Adrafinil may adversely affect your liver. If you already have a fatty or scarred liver, please consult with your physician before taking Adrafinil.


It is absolutely imperative that you stick to the recommended dosage range when taking Adrafinil. The recommended dosage is 150 mg to 300 mg. Adrafinil should be administered in cycles and not taken on monthly bases, lest you develop a tolerance or addiction to the drug. Taking it in cycles can also decrease your chances of experiencing adverse side effects. As always, pop responsibly and emancipate your mind.

Erica Silva on Twitter
Erica Silva
Senior Editor
Erica Silva is a blogger by choice. She loves to discover the world around her. She likes to share her discoveries, experiences and express herself through her blogs. Currently, she is associated with DementiaTalk Team.

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