Aniracetam Side-Effects & Drug Interactions

Aniracetam Side-Effects

Aniracetam is a smart drug belonging to the Racetam family developed in Belgium during the 1970s. Common trade names for the drug include: Draganon, Sarpul, Ampamet, Memodrin and Referan. The drug has an excellent tolerability profile, however there are certain Aniracetam side effects to be aware of.

Side Effects of Aniracetam

  • Some of the most common Aniracetam side effects include headaches, pain, insomnia, vertigo, anxiety, diarrhea and nausea.


  • The most common side effect of this drug is headaches. The theory behind racetam headaches is that the drug uses up choline stores in the brain. Increased choline use may be the primary reason for this side effect. For this reason, some users suggest adding in a supplement that helps to replenish choline such as Alpha GPC.


  • Brain fog is another common Aniracetam side effect. The exact mechanism as to why brain fog occurs is unclear. One theory is that the drug’s modulation of acetylcholine indirectly causes this. If you experience brain-fog, it is advised to lower the dosage and observe the effects. Discontinue if the side effect continues.


  • Irritability is another common Aniracetam side effect. The cause of irritability is unknown but could be a result of the drugs interaction with other neurotransmitters. This side effect only appears to affect a select group of users. Try lowering the dosage first and discontinue the drug if irritability continues.
  • Most of the common Aniracetam side effects occur with higher dosages of the nootropic. In order to reduce such side effects, users should start with a lower dosage or lower their current dosage. Some users are more sensitive to the drug than others so dosage should be chosen carefully.
  • Rare side effects such as allergic reactions are possible. It is recommended to do an “allergy test” first by consuming a very small amount of the nootropic. Allergic reactions can range from mild to severe. If you experience allergy symptoms such as rash, you are advised to contact a physician immediately.

Do not use Aniracetam if you are pregnant, breastfeeding or planning to become pregnant. There is not enough research to make a conclusion about safety for pregnant or nursing mothers

Aniracetam’s interaction with other drugs

  • Aniracetam couples well with cholinergic compounds. These compounds increase the level of choline in the brain. Choline boosting supplements might also help to reduce Aniracetam side effects such as headache.
  • Due to the drug’s fat solubility, the drug does not stack well with fat-blocking drugs. 
  • Aniracetam stacks well with other compounds of the racetam family. Keep in mind that adding racetam drugs might increase side effects.
  • Another well-known and easily stacked supplement is Alpha GPC. Alpha GPC replenishes choline in the brain. The combination might reduce headaches and further increase cognitive functioning.
  • Combination with antidepressant medication could increase the risk of side effects. The reason for this is due to the drugs effects on Serotonin. A slim chance of Serotonin Syndrome may exist although, no reports involving Aniracetam currently exist. It is always best to speak with a doctor if you are taking other medications.


  • The recommended Aniracetam dosage is 750 mg – 1500 mg. Many vendors carry the nootropic in capsules ranging from 500 mg – 1200 mg. 
  • Some users suggest an “attack dose” since the drug has cumulative effects. An attack dose is a technique used in order to get positive effects quicker. Using attack dosages is ill-advised for beginners due to the higher risk of negative Aniracetam side effects.
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Erica Silva
Senior Editor
Erica Silva is a blogger by choice. She loves to discover the world around her. She likes to share her discoveries, experiences and express herself through her blogs. Currently, she is associated with DementiaTalk Team.

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